I-Carbapenem-resistant OXA-48 Detection K-Set (Lateral Flow Assay)
Isingeniso Somkhiqizo
I-Carbapenem-resistant OXA-48 Detection K-Set (Lateral Flow Assay) iwuhlelo lokuhlola lwe-immunochromatographic oluhloselwe ukutholwa kwekhwalithi ye-OXA-48-type carbapenemase emakoloni amagciwane.Isivivinyo siwukuhlolwa kwelabhorethri yokusebenzisa incwadi kadokotela engasiza ekuxilongweni kwezinhlobo ze-carbapenem ezimelana nohlobo lwe-OXA-48.
Izici
| Igama | I-Carbapenem-resistant OXA-48 Detection K-Set (Lateral Flow Assay) |
| Indlela | I-Lateral Flow Assay |
| Uhlobo lwesampula | Amakoloni amagciwane |
| Ukucaciswa | Izivivinyo ezingama-25/ikhithi |
| Isikhathi sokutholwa | 10-15 imiz |
| Izinto zokutholwa | I-Enterobacteriaceae engamelana ne-Carbapenem (CRE) |
| Uhlobo lokutholwa | I-OXA-48 |
| Ukuzinza | I-K-Set izinzile iminyaka emi-2 ku-2°C-30°C |
Inzuzo
- Ngokushesha
Thola umphumela phakathi kwemizuzu engu-15, izinsuku ezi-3 ngaphambi kwezindlela zokuthola ezivamile - I-SOXA-48le
Kulula ukuyisebenzisa, abasebenzi baselabhorethri abajwayelekile bangasebenza ngaphandle kokuqeqeshwa - Inembile
Ukuzwela okuphezulu nokucacisa
Umkhawulo wokutholwa ophansi: 0.10 ng/mL
Iyakwazi ukubona iningi lezinhlobo ezingaphansi ezivamile ze-OXA-48
- Umphumela onembile
Asikho isidingo sokubala, umphumela wokufunda obonwayo - Ezomnotho
Umkhiqizo ungathuthwa futhi ugcinwe ekamelweni lokushisa, ukunciphisa izindleko
Ukubaluleka kokuhlolwa kwe-CRE
I-CRE, okusho ukuthi i-Enterobacteriaceae engamelana ne-carbapenem, iwumndeni wamagciwane okunzima ukuwelapha ngoba amelana kakhulu nama-antibiotics.Izinhlobo ze-Klebsiella kanye ne-Escherichia coli (E. coli) ziyizibonelo ze-Enterobacteriaceae, ingxenye evamile yebhaktheriya yamathumbu omuntu engakwazi ukumelana ne-carbapenem.Isizathu esenza ama-CRE amelana ne-carbapenems yingoba akhiqiza ama-carbapenemase.
Odokotela babamba iqhaza elibalulekile ekwehliseni ukusabalala kwe-CRE.Ngokuvamile, bangasiza ekuvimbeleni ukusabalala kwe-CRE nge
- Yazi ukuthi iziguli ezine-CRE zilaliswe esibhedlela noma zidluliselwe esikhungweni, futhi uhlale wazi amazinga okutheleleka nge-CRE.
- Beka iziguli okwamanje noma ezazikade zifakwe amakoloni noma ezingenwe yi-CRE ku-Contact Precautions.
- Qiniseka ukuthi amalebhu axwayisa ngokushesha abasebenzi basemtholampilo nabavimbela ukutheleleka lapho bekhonjwa i-CRE
- Nikeza futhi usebenzise ama-antibiotic ngokuhlakanipha
- Susa amadivayisi ahlaselayo ngokushesha lapho kungasadingeki
……
Ukuhlonza ngokushesha iziguli ezifakwe emakoloni noma ezingenwe yilezi zinambuzane futhi zibekwe kokuthi Izinyathelo Zokuthintana lapho kufaneleka, ukusebenzisa ama-antibiotic ngokuhlakanipha, kanye nokunciphisa ukusetshenziswa kwedivayisi zonke izingxenye ezibalulekile zokuvimbela ukudluliswa kwe-CRE, okusho ukuthi ukutholwa okusheshayo nokunembile kwe-CRE kuyadingeka kakhulu.
I-OXA-48-tye carbapenemase
I-Carbapenemase ibhekisela ohlotsheni lwe-β-lactamase olungase okungenani i-hydrolyze imipenem noma i-meropenem ngokuphawulekayo, kuhlanganise no-A, B, D izinhlobo ezintathu zama-enzyme ahlukaniswa ngesakhiwo se-Ambler samangqamuzana.I-Class D, njenge-OXA-type carbapenemase, yayivame ukutholwa ku-Acinetobacteria.Ucwaningo lokuhlola lubonise ukuthi i-OXA-48-type carbapenemases, eyaziwa nangokuthi i-oxacillinase-48-like beta-lactamase, ayi-carbapenemase evame kakhulu e-Enterobacterales ezindaweni ezithile zomhlaba futhi yethulwa njalo ezifundeni ezingenasici, lapho bebhekene nokuqubuka kwe-nosocomial.
Ukusebenza
- Engeza amaconsi angu-5 esixazululo sokwelashwa okuyisampula
- Dip amakholoni ebhaktheriya nge-loop yokugoma elahlwayo
- Faka iluphu kushubhu
- Engeza u-50 μL emthonjeni we-S, linda imizuzu engu-10-15
- Funda umphumela
Oda Ulwazi
| Imodeli | Incazelo | Ikhodi yomkhiqizo |
| I-CPO48-01 | Izivivinyo ezingama-25/ikhithi | I-CPO48-01 |
