I-VIM-resistant VIM Detection K-Set (Lateral Flow Assay) Isithombe Esifakiwe

I-K-Set ye-VIM engamelana ne-Carbapenem (I-Lateral Flow Assay)

Ukuhlolwa okusheshayo kohlobo lwe-VIM kungakapheli imizuzu eyi-10-15

Izinto zokutholwa	I-Enterobacteriaceae engamelana ne-Carbapenem (CRE)
Indlela yokwenza	I-Lateral Flow Assay
Uhlobo lwesampula	Amakoloni amagciwane
Imininingwane	Izivivinyo ezingama-25/ikhithi
Ikhodi yomkhiqizo	I-CPV-01

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isingeniso Somkhiqizo

I-Carbapenem-resistant VIM Detection K-Set (Lateral Flow Assay) iwuhlelo lokuhlola lwe-immunochromatographic oluhloselwe ukutholwa kwekhwalithi ye-VIM-type carbapenemase kumakoloni ebhaktheriya.Isivivinyo siwukuhlolwa kwelabhorethri yokusebenzisa incwadi kadokotela engasiza ekuxilongweni kwezinhlobo ze-VIM ezimelana ne-carbapenem.

I-Carbapenem-resistant NDM Detection K-Set (Lateral Flow Assay) 1

Izici

Igama	I-K-Set ye-VIM engamelana ne-Carbapenem (I-Lateral Flow Assay)
Indlela	I-Lateral Flow Assay
Uhlobo lwesampula	Amakoloni amagciwane
Ukucaciswa	Izivivinyo ezingama-25/ikhithi
Isikhathi sokutholwa	10-15 imiz
Izinto zokutholwa	I-Enterobacteriaceae engamelana ne-Carbapenem (CRE)
Uhlobo lokutholwa	I-VIM
Ukuzinza	I-K-Set izinzile iminyaka emi-2 ku-2°C-30°C

Inzuzo

Ngokushesha
Thola umphumela phakathi kwemizuzu engu-15, izinsuku ezi-3 ngaphambi kwezindlela zokuthola ezivamile
Kulula
Kulula ukuyisebenzisa, abasebenzi baselabhorethri abajwayelekile bangasebenza ngaphandle kokuqeqeshwa
Inembile
Ukuzwela okuphezulu nokucacisa
Umkhawulo wokutholwa ophansi: 0.20 ng/mL
Iyakwazi ukuthola iningi lezinhlobo ezingaphansi ezivamile ze-VIM

Umphumela onembile
Asikho isidingo sokubala, umphumela wokufunda obonwayo
Ezomnotho
Umkhiqizo ungathuthwa futhi ugcinwe ekamelweni lokushisa, ukunciphisa izindleko

Ukubaluleka kokuhlolwa kwe-CRE

I-Enterobacteriaceae engamelana ne-Carbapenem (CRE) iyingxenye yeqembu lamagciwane ahlala emathunjini abanye abantu.Ahlobene ne-E. coli, kodwa kuvamile ukuba ne-E. coli emathunjini akho nasesinqeni.Inkinga yenzeka lapho la magciwane eguquka futhi engazweli kuma-antibiotics.Amanye ama-CRE awazweli emithini eminingi kangangokuthi awalapheki, futhi kufika ingxenye yeziguli ezingenwe yilesi sifo zingase zife.Lokhu kuyakhathaza kakhulu ngoba i-carbapenems yayivame ukuba ngomunye wemithi elwa namagciwane engaphatha ngempumelelo enye “ama-superbugs” e-Enterobacter.

Izindlela ezijwayelekile ezithathwa ukulawula ukusabalala kwe-CRE:

Ukuqapha okuqinile kokutheleleka kwe-CRE
Ukuhlukaniswa kweziguli ngaphambi nangesikhathi sokulaliswa esibhedlela
Qaphela lapho unikeza ama-antibiotics, gwema ukusebenzisa kabi izidakamizwa
Sebenzisa izindlela eziyinyumba, geza izandla futhi ugweme ukuba ngaphakathi e-ICU isikhathi eside

……
Kungakho ukuthayipha kwangaphambi kwesikhathi kwama-subtypes e-CRE kubalulekile ekulawuleni i-CRE yomtholampilo.Amakhithi okuhlola e-CRE asheshayo futhi anembile angasiza ngencwadi yezokwelapha, ukuphathwa kwesiguli, ngaleyo ndlela kuncishiswe isivinini esikhulayo sokumelana nama-antibiotics.

I-VIM-Type Carbapenemase

I-Carbapenemase iwuhlobo lwe-β-lactamase olungase okungenani i-hydrolyze imipenem noma i-meropenem ngokuphawulekayo, kuhlanganise no-A, B, D izinhlobo ezintathu.Kulezi zinhlobo, i-Class B yi-metallo-β-lactamases (MBLs), kuhlanganise nama-carbapenemase afana ne-IMP, VIM kanye ne-NDM, atholakala kakhulu ku-Pseudomonas aeruginosa, i-Acinetobacteria kanye ne-Enterobacteriaceae bacteria.I-Verona Integron-encoded Metallo-beta-lactamase (VIM) iyi-carbapenemase evame ukuhlangana nayo e-P. aeruginosa3.Phakathi kwezinhlobonhlobo, i-VIM-2 metallo-beta-lactamase ibonisa ukusatshalaliswa kwendawo okubanzi kakhulu, okuhlanganisa nezwekazi laseYurophu.