I-Carbapenem-resistant OXA-23 Detection K-Set (Lateral Flow Assay) iwuhlelo lokuhlola lwe-immunochromatographic oluhloselwe ukutholwa kwekhwalithi ye-OXA-23-type carbapenemase emakoloni amagciwane.Isivivinyo siwukuhlolwa kwelabhorethri yokusebenzisa incwadi kadokotela engasiza ekuxilongweni kwezinhlobo ze-carbapenem ezimelana nohlobo lwe-OXA-23.
Igama | I-Carbapenem-resistant OXA-23 Detection K-Set (Lateral Flow Assay) |
Indlela | I-Lateral Flow Assay |
Uhlobo lwesampula | Amakoloni amagciwane |
Ukucaciswa | Izivivinyo ezingama-25/ikhithi |
Isikhathi sokutholwa | 10-15 imiz |
Izinto zokutholwa | I-Enterobacteriaceae engamelana ne-Carbapenem (CRE) |
Uhlobo lokutholwa | I-OXA-23 |
Ukuzinza | I-K-Set izinzile iminyaka emi-2 ku-2°C-30°C |
I-CRE (i-Carbapenem-resistant Enterobacteriaceae) iwumndeni wamagciwane okunzima ukuwaphatha ngoba amelana kakhulu nama-antibiotics.Ukutheleleka kwe-CRE kuvame ukwenzeka ezigulini ezibhedlela, emakhaya asebekhulile, nakwezinye izilungiselelo zezempilo.Iziguli ukunakekelwa kwazo okudinga amathuluzi afana nama-ventilator (imishini yokuphefumula), ama-catheter omchamo (isinye), noma ama-catheter afakwa emthanjeni (umthambo), kanye neziguli ezithatha izifundo ezinde zama-antibiotic athile zisengozini enkulu yokutheleleka nge-CRE.
Amanye amabhaktheriya e-CRE asengazweli kuma-antibiotic amaningi atholakalayo.Ukutheleleka kwalawa magciwane kunzima kakhulu ukuwelapha, futhi kungabulala—omunye umbiko uveza ukuthi kungaba nomthelela ekufeni ezigulini ezifika ku-50% ezingenwa yilesi sifo.
Ukuze uvimbele ukusakazeka okwengeziwe kwe-CRE, ukunakekelwa kwezempilo kufanele kuhlinzekwe
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Ukuhlonza ngokushesha iziguli ezine-CRE nokuzihlukanisa kwezinye iziguli ze-ICU lapho kufaneleka, ukusebenzisa ama-antibiotic ngokunengqondo, nokunciphisa ukusetshenziswa kwemishini ehlaselayo kubalulekile ekuvimbeleni ukudluliswa kwe-CRE.Ukuhlolwa okusheshayo kwe-CRE kuyisidingo esidingekayo sokuqaliswa kwalezi zindlela, okwenza kube yingxenye ebalulekile yokuphathwa kwe-CRE yomtholampilo.
I-Carbapenemase ibhekisela ohlotsheni lwe-β-lactamase olungase okungenani i-hydrolyze imipenem noma i-meropenem ngokuphawulekayo, kuhlanganise no-A, B, D izinhlobo ezintathu zama-enzyme ahlukaniswa ngesakhiwo se-Ambler samangqamuzana.I-Class D, njenge-OXA-type carbapenemase, yayivame ukutholwa ku-Acinetobacteria.Eminyakeni yakamuva, kube nemibiko yokulaliswa esibhedlela okubangelwa i-OXA-23, okungukuthi i-Oxacillinase-23-like beta-lactamase.Amaphesenti angama-80% e-Acinetobacteria baumannii amelana ne-carbapenem yasekhaya akhiqiza i-carbapenemase yohlobo lwe-OXA-23, okwenza ukwelashwa komtholampilo kube nzima kakhulu.
Imodeli | Incazelo | Ikhodi yomkhiqizo |
I-CPO23-01 | Izivivinyo ezingama-25/ikhithi | I-CPO23-01 |