(1,3)-β-D-Glucan iyingxenye yezindonga zamaseli wezinto eziningi eziphilayo ezikhunta.Ososayensi baphenya ukuthi kungenzeka yini ukuhlolwa kwe-BG kanye negalelo layo ekuhlonzweni kusenesikhathi kwezinhlobo ezahlukene zezifo ezikhuntayo ezihlaselayo (IFI) ezivame ukutholakala esikhungweni sokunakekela semfundo ephakeme.Amazinga e-serum e-BG eziguli ezingama-28 okutholwe ukuthi zine-IFI eyisithupha [13 probable invasive aspergillosis (IA), 2 proven IA, 2 zygomycosis, 3 fusariosis, 3 cryptococcosis, 3 candidaemia kanye 2 pneumocystosis] ahlolwa ngokubuyela emuva.Ukwehluka kwe-kinetic kumazinga we-serum ye-BG kusuka ezigulini eziyi-15 ezitholwe zine-IA zaqhathaniswa nalezo ze-galactomannan antigen (GM).Ezimweni ezingu-5⁄15 ze-IA, i-BG yayinesimo esihle ngaphambi kwe-GM (ukuphela kwesikhathi kusukela ezinsukwini ezi-4 kuye kwezingu-30), ezimweni ezingu-8⁄15, i-BG yayinempilo ngesikhathi esifanayo ne-GM futhi, ezimweni ezingu-2⁄15, i-BG yayinempilo. ngemuva kwe-GM.Kwezinye izifo ezinhlanu zokukhunta, i-BG yayinesimo esihle kakhulu ngesikhathi sokuxilongwa ngaphandle kwezimo ezimbili ze-zygomycosis kanye nesinye sezimo ezintathu ze-fusariosis.Lolu cwaningo, olubonisa umsebenzi ojwayelekile wesikhungo sokunakekelwa kwemfundo ephakeme, luqinisekisa ukuthi ukutholwa kwe-BG kungaba nentshisekelo ekuhlolweni kwe-IFI ezigulini ezinezifo ze-hematological.
Iphepha langempela elithathwe ku-APMIS 119: 280–286.
Isikhathi sokuthumela: Feb-25-2021