I-Carbapenem-resistant NDM Detection K-Set (Lateral Flow Assay) Isithombe Esifakiwe

Ukuthola i-K-Set ye-Carbapenem engamelana ne-Carbapenem (I-Lateral Flow Assay)

Ukuhlola okusheshayo kohlobo lwe-NDM phakathi kwemizuzu eyi-10-15

Izinto zokutholwa	I-Enterobacteriaceae engamelana ne-Carbapenem (CRE)
Indlela yokwenza	I-Lateral Flow Assay
Uhlobo lwesampula	Amakoloni amagciwane
Imininingwane	Izivivinyo ezingama-25/ikhithi
Ikhodi yomkhiqizo	I-CPN-01

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isingeniso Somkhiqizo

I-Carbapenem-resistant NDM Detection K-Set (Lateral Flow Assay) iwuhlelo lokuhlola lwe-immunochromatographic oluhloselwe ukutholwa kwekhwalithi ye-NDM-type carbapenemase kumakoloni ebhaktheriya.Ukuhlolwa kuwukuhlolwa kwelabhorethri yokusebenzisa incwadi kadokotela engasiza ekuxilongweni kwezinhlobo ze-carbapenem ezimelana nohlobo lwe-NDM.

I-Carbapenem-resistant NDM Detection K-Set (Lateral Flow Assay) 1

Izici

Igama	Ukuthola i-K-Set ye-Carbapenem engamelana ne-Carbapenem (I-Lateral Flow Assay)
Indlela	I-Lateral Flow Assay
Uhlobo lwesampula	Amakoloni amagciwane
Ukucaciswa	Izivivinyo ezingama-25/ikhithi
Isikhathi sokutholwa	10-15 imiz
Izinto zokutholwa	I-Enterobacteriaceae engamelana ne-Carbapenem (CRE)
Uhlobo lokutholwa	NDM
Ukuzinza	I-K-Set izinzile iminyaka emi-2 ku-2°C-30°C

Inzuzo

Ngokushesha
Thola umphumela phakathi kwemizuzu engu-15, izinsuku ezi-3 ngaphambi kwezindlela zokuthola ezivamile
Kulula
Kulula ukuyisebenzisa, abasebenzi baselabhorethri abajwayelekile bangasebenza ngaphandle kokuqeqeshwa
Inembile
Ukuzwela okuphezulu nokucacisa
Umkhawulo wokutholwa ophansi: 0.15 ng/mL
Iyakwazi ukuthola iningi lezinhlobo ezincane ezivamile ze-NDM

Umphumela onembile
Asikho isidingo sokubala, umphumela wokufunda obonwayo
Ezomnotho
Umkhiqizo ungathuthwa futhi ugcinwe ekamelweni lokushisa, ukunciphisa izindleko

Ukubaluleka kokuhlolwa kwe-CRE

I-Enterobacteriaceae (CRE) engamelana ne-Carbapenem wuhlobo lwamagciwane.Bangadala izifo ezinzima okungaba nzima ukukwelapha.I-CRE ithole igama layo ekutheni imelana ne-carbapenems.I-Carbapenems iyisigaba esithuthukisiwe sama-antibiotics.Zadalwa ngeminyaka yawo-1980 ukuze zisize ukwelapha amagciwane ayengeke alashwe ngamanye ama-antibiotic.Ama-antibiotics asetshenziselwa ukubulala izinhlobo ezithile zamagciwane.Kunezinhlobo eziningi zale mithi.Ngokuhamba kwesikhathi, amanye amagciwane angase angasabulawa yiwo.Lokhu kwaziwa ngokuthi ukumelana nama-antibiotic.Ukusabalala okusheshayo kwe-CRE kubangelwa ukusetshenziswa kabi kwezidakamizwa kanye nokuphathwa ngendlela engafanele kweziguli ze-CRE.Uma isimo singanakiwe, sizoba nomthelela omubi ekunakekelweni kwezempilo kwabantu, kwenze ukuthi ukwelashwa nokulawulwa kwezifo kube nzima nakakhulu.

Indlela evamile yokuvimbela ukusabalala kwe-CRE yilezi:

Ukuqapha izifo ze-CRE ngokuqinile ezibhedlela
Ukunciphisa izindlela zokwelapha ezihlaselayo ngokushesha
Hlukanisa iziguli ze-CRE
Nikeza ama-antibiotic kuphela uma edingeka ngempela
Ukusebenzisa amasu oyinyumba ukuze kuncishiswe ukusabalala

……
Kuyacaca ukubona ukubaluleka kokuhlolwa kwe-CRE kusenesikhathi kuzo zonke izindlela ezingenhla.Ukuhlolwa kokuxilonga okusheshayo nokunembile kubaluleke kakhulu ekuthayipheni kwangaphambi kwesikhathi kwezinhlobo ze-CRE, ukuqondiswa kwemithi, kanye nokuthuthukiswa kwamazinga ezokwelapha nempilo yabantu.

NI-DM-uhlobo carbapenemase

I-Carbapenemase ibhekisela ohlotsheni lwe-β-lactamase olungase okungenani i-hydrolyze imipenem noma i-meropenem ngokuphawulekayo, kuhlanganise no-A, B, D izinhlobo ezintathu zama-enzyme ahlukaniswa ngesakhiwo se-Ambler samangqamuzana.Phakathi kwazo, i-Class B yi-metallo-β-lactamases (MBLs), okuhlanganisa i-IMP, i-VIM ne-NDM, njll, ebizwa ngokuthi i-metalloenzyme, etholakala kakhulu ku-Pseudomonas aeruginosa, i-Acinetobacteria kanye ne-Enterobacteriaceae bacteria.Selokhu yabikwa okokuqala e-India ngo-2008, i-NDM (i-New Delhi metallo-beta-lactamase) isabalale emhlabeni wonke ngezinga elishaqisayo.Kuze kube manje, i-NDM isivele emazweni amaningi eYurophu, e-United States, eCanada naseMexico eNyakatho Melika, nasemazweni ase-Asia afana neChina, Japan, South Korea kanye neSingapore.Emazweni afana ne-India ne-Pakistan, i-NDM ibangele ubhubhane, ngezinga lokutholwa elingu-38.5%.Ukwenza imikhiqizo yokuxilonga ye-carbapenemase esheshayo ibaluleke kakhulu ekuthayipheni kwangaphambi kwesikhathi kwezinhlobo ezimelana nezidakamizwa, ukuqondiswa kwemithi, kanye nokuthuthukiswa kwamazinga ezokwelapha nempilo yabantu.