I-Aspergillus Galactomannan ELISA Detection Kit
Isingeniso Somkhiqizo
I-FungiXpert® Aspergillus Galactomannan ELISA Detection Kit iyi-assay ye-immunosorbent exhunywe yi-Enzyme ukuze kutholwe ikhwalithi ye-Aspergillus galactomannan antigen kumasampuli e-serum yabantu abadala neyezingane kanye namasampula oketshezi lwe-bronchoalveolar lavage (BAL).
Izigameko ze-Invasive Aspergillosis (IA) ezigulini ezingenawo amandla omzimba zikhula ngokushesha ngenxa yokusetshenziswa kabi kwama-antibiotic.I-IA inezinga eliphezulu lokufa ngenxa yokuntuleka kokubonakaliswa komtholampilo okujwayelekile kanye nezindlela zokuxilongwa kusenesikhathi ezisebenzayo.I-Aspergillus fumigatus ingelinye lamagciwane ajwayeleke kakhulu abangela ukutheleleka nge-aspergillus okunzima ezigulini ezinesifo sokuzivikela komzimba, kulandele i-Aspergillus flavus, i-Aspergillus niger ne-Aspergillus terreus.
Izici
| Igama | I-Aspergillus Galactomannan ELISA Detection Kit |
| Indlela | ELISA |
| Uhlobo lwesampula | I-Serum, uketshezi lwe-BAL |
| Ukucaciswa | 96 ukuhlolwa/ikhithi |
| Isikhathi sokutholwa | 2 h |
| Izinto zokutholwa | I-Aspergillus spp. |
| Ukuzinza | Ikhithi izinzile unyaka ongu-1 ku-2-8°C |
| Umkhawulo wokutholwa ophansi | 0.5 ng/mL |
Ingemuva
I-Aspergillosis ehlaselayo (IA)
Abathintekayo
Iziguli ezine-neutropenia ende, ezilandela ukufakelwa kabusha noma ngokuhlangana nemithi enolaka ye-immunosuppressive.
Izehlakalo eziphezulu
5% kuya ku-20%, kuye ngenani leziguli.
Izinga lokufa eliphezulu
50% kuya ku-80% ngenxa yengxenye yokukhula ngokushesha kokutheleleka (okungukuthi, amasonto angu-1-2 kusukela ekuqaleni kuya ekufeni).
Kunzima ukuxilonga
Kunzima ukuthola ubufakazi be-histopathological.Ukuzwela kwesiko kuphansi.≈30% wamacala ahlala engaxilongwa futhi engelashwa lapho efa.
Ukuhlolwa kwe-Galactomannan (GM).
- I-antigen ethize ye-aspergillus etholakala odongeni lweseli ekhishwa ngesikhathi sokukhula kwe-aspergillosis ehlaselayo.
- Ezinsukwini ezingu-7 kuya kweziyi-14 ngaphambi kokuba ezinye izinkomba zokuxilonga zibonakale.
Isimiso
Izinzuzo
- I-Advance eyengeziwe
Indlela yokutholwa konqenqema ehamba phambili emhlabeni jikelele, ukuzwela okuphezulu kanye nokucacisa - Okunembe Kakhulu
Lungiselela inqubo yokusebenza.Yehlisa ubungozi bokungcola ngesikhathi sokuhlolwa - Ngokushesha
Ukutholwa kwesinyathelo esisodwa, ukunciphisa inani lokufukamela kanye nesikhathi sokugeza
- Okuningi Kwezomnotho
Hlukanisa i-microplate, ukonga izindleko - Izincomo
Kunconywe umhlahlandlela we-IDSA we-Aspergillosis 2016 kanye nomhlahlandlela we-ESCMID-ECMM-ERS we-Aspergillosis 2018
Umphumela womtholampilo
Ukuxilongwa kusenesikhathi
- I-GM iyizinsuku ezingu-5-8 ngaphambi kwezimpawu zomtholampilo ze-aspergillosis (IA);
- I-GM iyizinsuku ezingu-7.2 ngaphambi kwe-CT scan yokulungiswa okuphezulu;
- I-GM iyizinsuku eziyi-12.5 ngaphambi kokuqala kokwelashwa kwe-empirical antifungal.
Ukuqapha okunamandla
- I-GM ilingana nenani lesikhunta, elingabonisa izinga lokutheleleka.
- Okuqukethwe kwe-GM antigen kwehla ngokusetshenziswa kwezidakamizwa ze-antifungal.
Isisekelo sezokwelapha esibalulekile
- Yehlisa ukusetshenziswa kwe-empirical antifungal treatment.
- Ukuxhumana okuqinile phakathi komphumela kanye nenkomba ye-GM yomdlavuza we-hematological.
Ukutholwa okuhlangene kokuhlolwa kwe-G kanye ne-GM
- Ukucaciswa okuphezulu kanye nevelu yokubikezela okuhle
- Ukuzwela okuphezulu
Oda Ulwazi
| Imodeli | Incazelo | Ikhodi yomkhiqizo |
| I-GMKT-01 | 96 ukuhlolwa/ikhithi | I-FGM096-001 |
